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Caused by bacteria Mycobacterium tuberculosis CAUSES Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but TB bacteria can attack any part of the body such as the kidney, spine, and brain. Not everyone infected with TB becomes sick. Some people develop TB disease soon after becoming infected (within weeks) before their immune system can fight the TB germs. Other people have latent TB infection and may get sic